Benign mimics of prostate cancer

The histopathological diagnosis of prostatic adenocarcinoma is challenged by the existence numerous benign mimics. Most these lesions have no clinical significance and many do not need to be reported. Their relevance lies in risk that they are misinterpreted as cancer. This review presents features mimics discusses their distinction from most often misdiagnosed cancer atrophy its variants, including simple atrophy, partial post-atrophic hyperplasia. Benign proliferations a group with crowded small glands or little nuclear atypia. problematic entity this adenosis, which may more alarming architecture than some cancers. A diagnostic problem several discontinuous absent basal cell layer. Hyperplastic metaplastic include Basal hyperplasia especially mimic prostate dark glands, variable atypia pseudoinfiltrative pattern, present. anatomical structure causes problems seminal vesicle. mucosa vesicle contains acini, very pronounced Pathologists familiar mimics, false positive lead unnecessary radical treatment.